I just think that Darwinian evolution defies the spirit of science itself, if you look at that spirit as reductionism itself.
I guess it depends on the type of reductionism yoy're talking about. I like what Daniel Dennet says about "greedy reductionism." It attempts to explain too much with too little, in the same way that creationism attempts to "explain" biology.
It seems to me that there is much, much more research on evolutionary biology, and and actual evidence for it - most particularly in the field of cellular development - than there is for "creation." However, if a creator exists, I'd be very interested for his discovery to be established because I (and a lot of scientists) have many, many scientific and philosophical questions for him.